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ALK
Anaplastic Lymphoma Kinase signaling stabilizes SLC3A2 expression via MARCH11 to promote neuroblastoma cell growth
Solute Carrier Family 3, Member 2 (SLC3A2 or 4F2hc) is a multifunctional glycoprotein that mediates integrin-dependent signaling, acts …
Wei-Yun Lai
,
Tzu-Po Chuang
,
Marcus Borenäs
,
Dan Emil Lind
,
Bengt Hallberg
,
Ruth Palmer
DOI
IGF1R Contributes to Cell Proliferation in ALK-Mutated Neuroblastoma with Preference for Activating the PI3K-AKT Signaling Pathway
Aberrant activation of anaplastic lymphoma kinase (ALK) by activating point mutation or amplification drives 5-12% of neuroblastoma …
Jikui Guan
,
Marcus Borenäs
,
Junfeng Xiong
,
Wei-Yun Lai
,
Ruth Palmer
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DOI
Chromosome Imbalances in Neuroblastoma—Recent Molecular Insight into Chromosome 1p-deletion, 2p-gain, and 11q-deletion Identifies New Friends and Foes for the Future
Neuroblastoma is the most common extracranial solid pediatric tumor, with around 15% childhood cancer-related mortality. High-risk …
Jikui Guan
,
Ruth Palmer
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