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    Wei-Yun Lai

    Wei-Yun Lai

    Postdoctoral Researcher

    Latest

    • RUVBL1 and RUVBL2 are druggable MYC effector regulators in neuroblastoma cells
    • Anaplastic Lymphoma Kinase signaling stabilizes SLC3A2 expression via MARCH11 to promote neuroblastoma cell growth
    • ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition
    • IGF1R Contributes to Cell Proliferation in ALK-Mutated Neuroblastoma with Preference for Activating the PI3K-AKT Signaling Pathway
    • ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression
    • Novel human-derived EML4-ALK fusion cell lines identify ribonucleotide reductase RRM2 as a target of activated ALK in NSCLC
    • ALK ligand ALKAL2 potentiates MYCN-driven neuroblastoma in the absence of ALK mutation
    • 11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma

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