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Ruth Palmer Lab
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    Marcus Borenäs

    Marcus Borenäs

    PhD student

    University of Gothenburg

    Marcus research interest are the Organ of Zuckekandl and the origin of Neuroblastoma. A true traveler that feels as home under 4 meters of snow in Northern Sweden as in New Zeeland on the southern hemisphere.

    Interests
    • Spatial Transcriptomics
    • Clinical relevance
    • Fishing
    Education
    • PhD Biomedicine, 2024

      Unviersity of Gothenburg

    • Medical Programme, 2016

      University of Gothenburg

    Latest

    • RUVBL1 and RUVBL2 are druggable MYC effector regulators in neuroblastoma cells
    • Spatial transcriptomics exploration of the primary neuroblastoma microenvironment in archived FFPE samples unveils novel paracrine interactions
    • Anaplastic Lymphoma Kinase signaling stabilizes SLC3A2 expression via MARCH11 to promote neuroblastoma cell growth
    • ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition
    • IGF1R Contributes to Cell Proliferation in ALK-Mutated Neuroblastoma with Preference for Activating the PI3K-AKT Signaling Pathway
    • ALK ligand ALKAL2 potentiates MYCN-driven neuroblastoma in the absence of ALK mutation
    • Analysis of ALK, MYCN, and the ALK ligand ALKAL2 (FAM150B/AUGalpha) in neuroblastoma patient samples with chromosome arm 2p rearrangements
    • Repotrectinib (TPX-0005) effectively reduces growth of ALK-driven neuroblastoma cells
    • Alectinib, an Anaplastic Lymphoma Kinase Inhibitor, Abolishes ALK Activity and Growth in ALK-Positive Neuroblastoma Cells

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